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A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors

AIDS · 1998 · Vol. 12(7) · pp. F51–F58
Andrew CarrKatherine SamarasSamantha BurtonMatthew LawJudith FreundDonald J. ChisholmDavid A. Cooper

Abstract

A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance is a common complication of HIV protease inhibitors. Diabetes mellitus is relatively uncommon.

HIV/AIDS drug development and treatmentHIV-related health complications and treatmentsHIV Research and TreatmentLipodystrophyInsulin resistanceMedicineProtease inhibitor (pharmacology)Human immunodeficiency virus (HIV)Internal medicineProteaseInsulinDiabetes mellitusEndocrinology

MeSH terms

AdultBody CompositionCross-Sectional StudiesDiabetes MellitusFemaleHumansHyperlipidemiasInsulin ResistanceLipodystrophyMaleRisk FactorsSyndromeHIV InfectionsHIV Protease InhibitorsSaquinavir
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