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New insights on the role of microglia in synaptic pruning in health and disease

Current Opinion in Neurobiology · 2015 · Vol. 36 · pp. 128–134
Soyon HongLasse Dissing‐OlesenBeth Stevens✉
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Neuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsNuclear Receptors and SignalingSynaptic pruningMicrogliaNeurosciencePruningDiseasePsychologyBiologyMedicineImmunologyInflammation

Funding

  • Alzheimer's Research Trust
  • Lundbeckfonden
  • National Institutes of Health
Citations
578
FWCI
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References
81
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100%
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References
High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation
Journal of Neuroscience · 2000 · 1,860 citations
Resting Microglia Directly Monitor the Functional State of Synapses<i>In Vivo</i>and Determine the Fate of Ischemic Terminals
Journal of Neuroscience · 2009 · 1,592 citations
Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
Annals of Neurology · 1991 · 4,370 citations
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
Science Translational Medicine · 2014 · 822 citations
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Nature Neuroscience · 2007 · 3,630 citations
Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease
Neuron · 2007 · 1,667 citations
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
Neuron · 2012 · 3,978 citations
Microglia Modulate Wiring of the Embryonic Forebrain
Cell Reports · 2014 · 663 citations
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