reviewTop 1% cited
Brain volume in first-episode schizophrenia
The British Journal of Psychiatry · 2006 · Vol. 188(6) · pp. 510–518
R. Grant Steen✉(University of North Carolina at Chapel Hill)Courtney Mull(University of North Carolina at Chapel Hill)Robert K. McClure(University of North Carolina at Chapel Hill)Robert M. Hamer(University of North Carolina at Chapel Hill)Jeffrey A. Lieberman(University of North Carolina at Chapel Hill)
Abstract
Average volumetric changes are close to the limit of detection by MRI methods. It remains to be determined whether schizophrenia is a neurodegenerative process that begins at about the time of symptom onset, or whether it is better characterised as a neurodevelopmental process that produces abnormal brain volumes at an early age.
Schizophrenia research and treatmentAdvanced Neuroimaging Techniques and ApplicationsFunctional Brain Connectivity StudiesBrain sizeSchizophrenia (object-oriented programming)Magnetic resonance imagingMedicineMeta-analysisNeuroimagingPsychologyPsychosisPsychiatryInternal medicine
MeSH terms
AdolescentAdultBrainCerebral VentriclesFemaleHippocampusHumansMagnetic Resonance ImagingMaleResearch DesignSchizophrenia
Citations
841
FWCI
29.95
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References
96
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100%
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Nature Neuroscience · 1999 · 5,548 citations
Meta-Analysis of Regional Brain Volumes in Schizophrenia
American Journal of Psychiatry · 2000 · 1,660 citations
The relationship between brain structure and neurocognition in schizophrenia: a selective review
Schizophrenia Research · 2004 · 422 citations
The neuropathology of schizophrenia
Brain · 1999 · 1,664 citations
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