article Open AccessTop 10% cited
Design, synthesis and in vitro antimalarial activity of an acylhydrazone library
Bioorganic & Medicinal Chemistry Letters · 2005 · Vol. 16(1) · pp. 31–35
Patricia Melnyk✉(Centre National de la Recherche Scientifique)Vincent Leroux(Centre National de la Recherche Scientifique)Christian Sergheraert(Université de Lille)Philippe Grellier
Malaria Research and ControlDrug-Induced Hepatotoxicity and ProtectionMosquito-borne diseases and controlChemistryPlasmodium falciparumIn vitroChloroquineChelationDeferoxamineCombinatorial chemistryPharmacologyChemical synthesisMalaria
MeSH terms
AnimalsAntimalarialsChelating AgentsChemistry, PharmaceuticalDeferoxamineDrug ResistanceEnzyme InhibitorsHumansHydrazonesIronModels, ChemicalPlasmodium falciparumTechnology, PharmaceuticalDrug DesignInhibitory Concentration 50
Funding
- Université de Lille
Citations
251
FWCI
5.38
field-weighted impact
References
23
Percentile
95%
vs. same field & year
Citations per year
References
Human Malaria Parasites in Continuous Culture
Science · 1976 · 7,934 citations
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
Antimicrobial Agents and Chemotherapy · 1979 · 2,501 citations
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
Journal of Immunological Methods · 1983 · 55,054 citations
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