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Novel IKK inhibitors: β-carbolines

Bioorganic & Medicinal Chemistry Letters · 2003 · Vol. 13(14) · pp. 2419–2422

Alfredo Castro(Millennium Engineering and Integration (United States))Lenny Dang(Millennium Engineering and Integration (United States))François Soucy(Millennium Engineering and Integration (United States))Louis Grenier(Millennium Engineering and Integration (United States))Hormoz Mazdiyasni(Millennium Engineering and Integration (United States))Maria Hottelet(Millennium Engineering and Integration (United States))Lana Parent(Millennium Engineering and Integration (United States))Christine Pien(Millennium Engineering and Integration (United States))Vito J. Palombella(Millennium Engineering and Integration (United States))Julian Adams✉(Millennium Engineering and Integration (United States))

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Natural product bioactivities and synthesis NF-κB Signaling Pathways Bioactive Compounds and Antitumor AgentsChemistryIκB kinasePhosphorylationKinasePharmacologyBETA (programming language)Natural productBiochemistryEnzymeNF-κB

MeSH terms

CarbolinesEnzyme InhibitorsHeLa CellsHumansPrecipitin TestsStructure-Activity RelationshipBlotting, WesternProtein Serine-Threonine KinasesElectrophoretic Mobility Shift AssayI-kappa B Kinase

Citations

241

FWCI

5.13

field-weighted impact

References

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96%

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