articleTop 1% cited
Effects of Coenzyme Q10 in Early Parkinson Disease
Archives of Neurology · 2002 · Vol. 59(10) · pp. 1541–1541
Clifford W. Shults✉(University of California, San Diego)
Abstract
Coenzyme Q10 was safe and well tolerated at dosages of up to 1200 mg/d. Less disability developed in subjects assigned to coenzyme Q10 than in those assigned to placebo, and the benefit was greatest in subjects receiving the highest dosage. Coenzyme Q10 appears to slow the progressive deterioration of function in PD, but these results need to be confirmed in a larger study.
Coenzyme Q10 studies and effectsParkinson's Disease Mechanisms and TreatmentsNuclear Receptors and SignalingCoenzyme Q10PlaceboDoseMedicineParkinson's diseaseInternal medicineRating scaleLevodopaPhysical therapyPsychology
MeSH terms
Administration, OralAgedAntioxidantsCoenzymesDose-Response Relationship, DrugDouble-Blind MethodFemalePersons with DisabilitiesDisabled PersonsHumansMaleMiddle AgedParkinson DiseaseUbiquinoneTreatment Outcome
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