articleTop 1% cited
Relating protein pharmacology by ligand chemistry
Nature Biotechnology · 2007 · Vol. 25(2) · pp. 197–206
Michael J. Keiser✉(University of California, San Francisco)Bryan L. Roth(University of North Carolina at Chapel Hill)Blaine N. Armbruster(University of North Carolina at Chapel Hill)Paul Ernsberger(National Institute of Mental Health)John J. Irwin(University of California, San Francisco)Brian K. Shoichet(University of California, San Francisco)
Computational Drug Discovery MethodsReceptor Mechanisms and SignalingChemical Synthesis and AnalysisLigand (biochemistry)Similarity (geometry)Computational biologyG protein-coupled receptorChemistryDrug discoveryReceptorBiologyBiochemistryComputer science
MeSH terms
Binding SitesPharmaceutical PreparationsLigandsProtein BindingProteinsDrug DesignSequence AlignmentDrug Delivery SystemsSequence Analysis, ProteinProtein Interaction MappingDatabases, Protein
Funding
- Johns Hopkins University
Citations
2,328
FWCI
59.89
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References
49
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100%
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Genome Research · 2003 · 53,132 citations
Similarity and clustering in chemical information systems
European Journal of Medicinal Chemistry · 1987 · 447 citations
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