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What is physiologic complexity and how does it change with aging and disease?

Neurobiology of Aging · 2002 · Vol. 23(1) · pp. 23–26

Ary L. Goldberger✉(Harvard University)Chung‐Kang Peng(Harvard University)Lewis A. Lipsitz(Hadassah Medical Center)

View via DOI Publisher page

Muscle activation and electromyography studies Neuroscience and Neural Engineering EEG and Brain-Computer InterfacesVastus medialisIsometric exerciseElectromyographyPhysical medicine and rehabilitationMedicineAnterior cruciate ligamentRecurrence quantification analysisPhysical therapyPsychologyAnatomy

MeSH terms

AgedAgingDiseaseHumansModels, NeurologicalNervous System Physiological Phenomena

Funding

National Heart, Lung, and Blood Institute
National Center for Research Resources

Citations

858

FWCI

9.54

field-weighted impact

References

34

Percentile

99%

vs. same field & year

Citations per year

Cited by

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References

Physiological time-series analysis: what does regularity quantify?

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Physiological time-series analysis using approximate entropy and sample entropy

American Journal of Physiology-Heart and Circulatory Physiology · 2000 · 7,644 citations

Approximate entropy as a measure of system complexity.

Proceedings of the National Academy of Sciences · 1991 · 5,695 citations

Gait variability and basal ganglia disorders: Stride‐to‐stride variations of gait cycle timing in parkinson's disease and Huntington's disease

Movement Disorders · 1998 · 898 citations

Is walking a random walk? Evidence for long-range correlations in stride interval of human gait

Journal of Applied Physiology · 1995 · 844 citations

Altered fractal dynamics of gait: reduced stride-interval correlations with aging and Huntington’s disease

Journal of Applied Physiology · 1997 · 827 citations

Age-related alterations in the fractal scaling of cardiac interbeat interval dynamics

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1996 · 693 citations

PhysioBank, PhysioToolkit, and PhysioNet

Circulation · 2000 · 14,211 citations

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