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Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons

Neuroscience · 2001 · Vol. 107(1) · pp. 13–24

Alain Destexhe✉(Laboratoire de Neurobiologie Cellulaire et Moléculaire)Michael Rudolph(Laboratoire de Neurobiologie Cellulaire et Moléculaire)Jean‐Marc Fellous(Howard Hughes Medical Institute)Terrence J. Sejnowski(Salk Institute for Biological Studies)

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Neural dynamics and brain function stochastic dynamics and bifurcation Neuroscience and Neuropharmacology ResearchNeuroscienceGlutamatergicConductanceGABAergicIn vivoMembrane potentialPatch clampNeurotransmissionBiophysicsCurrent clamp

MeSH terms

Action PotentialsAnimalsCatsCell CompartmentationDendritesgamma-Aminobutyric AcidIon ChannelsModels, NeurologicalNerve NetNeural InhibitionSynaptic TransmissionOrgan Culture TechniquesStochastic ProcessesSynapsesTetrodotoxin

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680

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10.72

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99%

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Adaptive Exponential Integrate-and-Fire Model as an Effective Description of Neuronal Activity