reviewTop 10% cited

Apoptotic and antiapoptotic mechanisms in stroke

Cell and Tissue Research · 2000 · Vol. 301(1) · pp. 173–187

Mark P. Mattson✉(National Institute on Aging)Carsten Culmsee(National Institute on Aging)Zai Fang Yu(National Institute on Aging)

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Cell death mechanisms and regulation Neuroinflammation and Neurodegeneration Mechanisms Natural Compounds in Disease TreatmentCell biologyBiologyProgrammed cell deathApoptosisCalcium signalingCytochrome cOxidative stressSignal transductionMitochondrionCREB

MeSH terms

AnimalsBrainCalciumCarrier ProteinsCell NucleusBrain IschemiaHumansMitochondriaModels, BiologicalNerve Growth FactorsNeuronsSignal TransductionGene ExpressionCytokinesApoptosis

Citations

316

FWCI

7.57

field-weighted impact

References

121

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98%

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References

Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: Evidence for a preconditioning mechanism

Journal of Neuroscience Research · 1999 · 362 citations

Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family

Journal of Cerebral Blood Flow & Metabolism · 1998 · 546 citations

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

Neuron · 1995 · 1,882 citations

A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide

Journal of Neurochemistry · 1997 · 775 citations

Role of Oxidants in Ischemic Brain Damage

Stroke · 1996 · 1,037 citations

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca<sup>2+</sup> Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

Journal of Neurochemistry · 1995 · 616 citations

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

Neuroscience Letters · 1993 · 481 citations

The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis

Experimental Neurology · 1999 · 439 citations

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