review Open AccessTop 1% cited
Mutation Frequencies and Antibiotic Resistance
Antimicrobial Agents and Chemotherapy · 2000 · Vol. 44(7) · pp. 1771–1777
José Luis Martínez✉Fernando Baquero(Hospital Universitario Ramón y Cajal)
Abstract
Antibiotic resistance can be achieved by horizontal acquisition of resistance genes (carried by plasmids or transposons), by recombination of foreign DNA into the chromosome, or by mutations in different chromosomal loci ([15][1]). In studies of molecular evolutionary biology, the term mutation rate
Evolution and Genetic DynamicsGenomics and Phylogenetic StudiesAntibiotic Resistance in BacteriaGeneticsTransposable elementPlasmidBiologyMutationMicrobial geneticsChromosomeAntibiotic resistanceGeneRecombination
MeSH terms
Anti-Bacterial AgentsBacteriaDrug Resistance, MicrobialGene FrequencyMutationSelection, GeneticGene Dosage
Citations
697
FWCI
13.44
field-weighted impact
References
78
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99%
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References
REPLICA PLATING AND INDIRECT SELECTION OF BACTERIAL MUTANTS
Journal of Bacteriology · 1952 · 1,360 citations
A functional classification scheme for beta-lactamases and its correlation with molecular structure
Antimicrobial Agents and Chemotherapy · 1995 · 2,450 citations
MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE
Genetics · 1943 · 3,925 citations
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