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Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction

Thorax · 2008 · Vol. 63(12) · pp. 1046–1051

MP Swanney✉(Christchurch Hospital)Gregg L Ruppel(Saint Louis University Hospital)Paul Enright(University of Arizona)Ole F. Pedersen(Aarhus University)Robert O. Crapo(University of Utah Hospital)Martin R. MillerRobert L. Jensen(LDS Hospital)Emanuela Falaschetti(University College London)J.P. Schouten(University of Groningen)J. Hankinson(Valdosta State University)Janet Stocks(University College London)Philip H. Quanjer(Erasmus University Rotterdam)

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Abstract

Airway obstruction should be defined by FEV(1)/FVC and FEV(1) being below the LLN using appropriate reference equations.

Chronic Obstructive Pulmonary Disease (COPD) Research Respiratory Support and Mechanisms Asthma and respiratory diseasesMedicineAirway obstructionPopulationNational Health and Nutrition Examination SurveyVital capacityAsymptomaticCOPDInternal medicineAirwayDemography

MeSH terms

AdolescentAdultAgedAged, 80 and overDiagnostic ErrorsFemaleForced Expiratory VolumeHumansMaleMiddle AgedPredictive Value of TestsReference ValuesVital CapacityPractice Guidelines as TopicPulmonary Disease, Chronic Obstructive

Citations

532

FWCI

23.26

field-weighted impact

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Percentile

100%

vs. same field & year

Citations per year

Cited by

ERS/ATS technical standard on interpretive strategies for routine lung function tests