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Utility, Limitations, and Pitfalls in Measuring Testosterone: An Endocrine Society Position Statement

The Journal of Clinical Endocrinology & Metabolism · 2006 · Vol. 92(2) · pp. 405–413
William RosnerRichard J. AuchusRicardo AzzizPatrick M. SlussHershel Raff

Abstract

Laboratory proficiency testing should be based on the ability to measure accurately and precisely samples containing known concentrations of testosterone, not only on agreement with others using the same method. When such standardization is in place, normative values for total and free testosterone should be established for both genders and children, taking into account the many variables that influence serum testosterone concentration.

Hormonal and reproductive studiesOvarian function and disordersSperm and Testicular FunctionPosition statementEndocrine systemStatement (logic)Testosterone (patch)Position (finance)MedicineEpistemologyEndocrinologyPhilosophyBusiness

MeSH terms

Chemistry, ClinicalEndocrine System DiseasesEndocrinologyHumansReference ValuesTestosterone

Funding

  • Quest Diagnostics
  • Abbott Diagnostics
Citations
1,149
FWCI
30.09
field-weighted impact
References
60
Percentile
100%
vs. same field & year
Citations per year
References
SEX‐HORMONE‐BINDING GLOBULIN
Clinical Endocrinology · 1974 · 1,130 citations
A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
The Journal of Clinical Endocrinology & Metabolism · 1999 · 3,683 citations
Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men
The Journal of Clinical Endocrinology & Metabolism · 2001 · 2,668 citations
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