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Comorbidities and Risk of Mortality in Patients with Chronic Obstructive Pulmonary Disease

American Journal of Respiratory and Critical Care Medicine · 2012 · Vol. 186(2) · pp. 155–161

Miguel Divo✉(Brigham and Women's Hospital)Claudia Côté(University of South Florida)Juan P. de‐Torres(Clinica Universidad de Navarra)Ciro Casanova(Universidad de La Laguna)José M. Marı́n(Hospital Universitario Miguel Servet)Víctor Pinto-Plata(Brigham and Women's Hospital)Javier J. Zulueta(Clinica Universidad de Navarra)Carlos Cabrera(Hospital Universitario de Gran Canaria Doctor Negrín)Jorge Zagaceta(Clinica Universidad de Navarra)Gary M. Hunninghake(Brigham and Women's Hospital)Bartolomé R. Celli(Brigham and Women's Hospital)

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Abstract

Comorbidities are frequent in COPD and 12 of them negatively influence survival. A simple disease-specific comorbidities index (COTE) helps assess mortality risk in patients with COPD.

Chronic Obstructive Pulmonary Disease (COPD) Research Chronic Disease Management Strategies Respiratory Support and MechanismsMedicineCOPDBODE indexHazard ratioComorbidityInternal medicineConfidence intervalProportional hazards modelQuartileRisk of mortality

MeSH terms

AgedFemaleHumansMaleProspective StudiesRisk FactorsSpainUnited StatesComorbidityMultivariate AnalysisProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveKaplan-Meier Estimate

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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary