article Open AccessTop 1% cited
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
Annals of the Rheumatic Diseases · 2007 · Vol. 66(9) · pp. 1162–1167
Naoki Nishimoto✉(Osaka University)Jun Hashimoto(Osaka University)N. Miyasaka(Tokyo Medical and Dental University)Kazuhiko Yamamoto(The University of Tokyo)Shinichi Kawai(Toho University Omori Medical Center)Tsutomu Takeuchi(Social Insurance Saitama Chuo Hospital)N. Murata(Rakuwakai Otowa Hospital)D. van der Heijde(Maastricht University)Tadamitsu Kishimoto(Osaka University)
Rheumatoid Arthritis Research and TherapiesAutoimmune and Inflammatory Disorders ResearchLymphoma Diagnosis and TreatmentTocilizumabMedicineRheumatoid arthritisInternal medicineRandomized controlled trialGastroenterologySurgery
MeSH terms
Interleukin-6 InhibitorsAdultAgedAnalysis of VarianceAntibodies, MonoclonalArthritis, RheumatoidBacterial InfectionsDouble-Blind MethodFemaleHumansMaleMethotrexateMiddle AgedRadiographySeverity of Illness Index
Funding
- Chugai Pharmaceutical
Citations
740
FWCI
48.08
field-weighted impact
References
45
Percentile
100%
vs. same field & year
Citations per year
Cited by
IL‐1, IL‐18, and IL‐33 families of cytokines
Immunological Reviews · 2008 · 892 citations
Tocilizumab: A Review in Rheumatoid Arthritis
Drugs · 2017 · 403 citations
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
Annals of the Rheumatic Diseases · 2009 · 804 citations
IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF- and IL-17
Lara D. Veeken · 2008 · 352 citations
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
Annals of the Rheumatic Diseases · 2008 · 1,104 citations
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update
Annals of the Rheumatic Diseases · 2017 · 5,757 citations
Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines
Frontiers in Immunology · 2018 · 1,234 citations
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update
Annals of the Rheumatic Diseases · 2013 · 1,756 citations
References
Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis
European Journal of Immunology · 1988 · 789 citations
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
Arthritis & Rheumatism · 1988 · 19,868 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
