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Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.

Stroke · 1993 · Vol. 24(1) · pp. 35–41

Harold P. Adams✉(University of Iowa)Birgitte H. Bendixen(University of Iowa)L. Jaap Kappelle(University of Iowa)José Biller(University of Iowa)Betsy B. Love(University of Iowa)David Gordon(University of Iowa)E. Eugene Marsh(University of Iowa)

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Abstract

The TOAST stroke subtype classification system is easy to use and has good interobserver agreement. This system should allow investigators to report responses to treatment among important subgroups of patients with ischemic stroke. Clinical trials testing treatments for acute ischemic stroke should include similar methods to diagnose subtypes of stroke.

Acute Ischemic Stroke Management Neurological Disorders and Treatments Cerebrovascular and Carotid Artery DiseasesMedicineEtiologyStroke (engine)Acute strokeClinical trialInternal medicineMedical diagnosisPhysical therapyPediatricsPathology

MeSH terms

AnticoagulantsArteriosclerosisCerebral InfarctionBrain IschemiaChondroitin SulfatesDermatan SulfateDiagnosis, DifferentialEmbolismGlycosaminoglycansHeparinoidsHeparan SulfateHeparitin SulfateHumans

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