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Relationship of Interleukin-6 and Tumor Necrosis Factor- With Muscle Mass and Muscle Strength in Elderly Men and Women: The Health ABC Study
The Journals of Gerontology Series A · 2002 · Vol. 57(5) · pp. M326–M332
Marjolein Visser✉(Amsterdam UMC Location VUmc)M. Pahor(Vrije Universiteit Amsterdam)Dennis R. Taaffe(Vrije Universiteit Amsterdam)Bret H. Goodpaster(Vrije Universiteit Amsterdam)Eleanor M. Simonsick(Vrije Universiteit Amsterdam)Anne B. Newman(Vrije Universiteit Amsterdam)M. Nevitt(Vrije Universiteit Amsterdam)Tamara B. Harris(Vrije Universiteit Amsterdam)
Abstract
Higher plasma concentrations of IL-6 and TNF-alpha are associated with lower muscle mass and lower muscle strength in well-functioning older men and women. Higher cytokine levels, as often observed in healthy older persons, may contribute to the loss of muscle mass and strength that accompanies aging.
Nutrition and Health in AgingBody Composition Measurement TechniquesExercise and Physiological ResponsesMedicineIsometric exerciseGrip strengthMuscle massSarcopeniaMuscle strengthCytokineInternal medicineTumor necrosis factor alphaInterleukin 6
MeSH terms
AgedAgingFemaleHumansKneeMaleTumor Necrosis Factor-alphaInterleukin-6Muscle, SkeletalHand StrengthBlack PeopleWhite People
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1,254
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