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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Nature Immunology · 2005 · Vol. 6(10) · pp. 981–988
Taro KawaiKen TakahashiShintaro SatoCevayir CobanHimanshu KumarHiroki KatoKen J. IshiiOsamu TakeuchiShizuo Akira
interferon and immune responsesImmune Response and InflammationCytokine Signaling Pathways and InteractionsIRF3MDA5IRF7InterferonInterferon regulatory factorsBiologyGene knockdownSignal transducing adaptor proteinRIG-IInterferon type I

MeSH terms

DEAD Box Protein 58Interferon-Induced Helicase, IFIH1Amino Acid SequenceAnimalsCells, CulturedDNA-Binding ProteinsHumansInterferon InducersInterferon Type IMolecular Sequence DataReceptors, ImmunologicRNA, MessengerTranscription FactorsVesicular stomatitis Indiana virusNF-kappa B
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