articleTop 1% cited
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
Nature Immunology · 2005 · Vol. 6(10) · pp. 981–988
Taro Kawai✉(Japan Science and Technology Agency)Ken Takahashi(Kyoto University)Shintaro Sato(Japan Science and Technology Agency)Cevayir Coban(Osaka University)Himanshu Kumar(Osaka University)Hiroki Kato(Osaka University)Ken J. Ishii(Osaka University)Osamu Takeuchi(Japan Science and Technology Agency)Shizuo Akira(Osaka University)
interferon and immune responsesImmune Response and InflammationCytokine Signaling Pathways and InteractionsIRF3MDA5IRF7InterferonInterferon regulatory factorsBiologyGene knockdownSignal transducing adaptor proteinRIG-IInterferon type I
MeSH terms
DEAD Box Protein 58Interferon-Induced Helicase, IFIH1Amino Acid SequenceAnimalsCells, CulturedDNA-Binding ProteinsHumansInterferon InducersInterferon Type IMolecular Sequence DataReceptors, ImmunologicRNA, MessengerTranscription FactorsVesicular stomatitis Indiana virusNF-kappa B
Citations
2,532
FWCI
38.28
field-weighted impact
References
39
Percentile
100%
vs. same field & year
Citations per year
Cited by
Interferon-Stimulated Genes: A Complex Web of Host Defenses
Annual Review of Immunology · 2014 · 3,035 citations
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
The Journal of Experimental Medicine · 2008 · 1,542 citations
Innate immunity to virus infection
Immunological Reviews · 2008 · 1,214 citations
Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures
Journal of General Virology · 2007 · 1,551 citations
Innate Immune Pattern Recognition: A Cell Biological Perspective
Annual Review of Immunology · 2015 · 1,401 citations
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
Clinical Microbiology Reviews · 2009 · 3,020 citations
Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity
Journal of Virology · 2007 · 1,038 citations
Toll-like receptors and innate immunity
Biochemical and Biophysical Research Communications · 2009 · 1,162 citations
References
Toll-like receptor signalling
Nature reviews. Immunology · 2004 · 8,188 citations
Toll-Like Receptors
Annual Review of Immunology · 2003 · 6,131 citations
Innate Immune Recognition
Annual Review of Immunology · 2002 · 8,305 citations
Cell Type-Specific Involvement of RIG-I in Antiviral Response
Immunity · 2005 · 1,338 citations
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
Nature Immunology · 2004 · 3,850 citations
IKKε and TBK1 are essential components of the IRF3 signaling pathway
Nature Immunology · 2003 · 2,672 citations
Regulating Intracellular Antiviral Defense and Permissiveness to Hepatitis C Virus RNA Replication through a Cellular RNA Helicase, RIG-I
Journal of Virology · 2005 · 888 citations
Cutting Edge: A Novel Toll/IL-1 Receptor Domain-Containing Adapter That Preferentially Activates the IFN-β Promoter in the Toll-Like Receptor Signaling
The Journal of Immunology · 2002 · 1,222 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
