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Biocompatibility index of antiseptic agents by parallel assessment of antimicrobial activity and cellular cytotoxicity

Journal of Antimicrobial Chemotherapy · 2008 · Vol. 61(6) · pp. 1281–1287
G. MüllerAxel Krämer

Abstract

The BI presented may be a useful tool to evaluate antiseptic agents for use in clinical practice.

Antimicrobial agents and applicationsPharmaceutical and Antibiotic Environmental ImpactsBacterial biofilms and quorum sensingBenzalkonium chlorideAntisepticCytotoxicityStaphylococcus aureusBiocompatibilityTriclosanCetylpyridinium chlorideChemistryAntimicrobialSilver sulfadiazine

MeSH terms

AnimalsAnti-Infective Agents, LocalDrug Evaluation, PreclinicalEscherichia coliFibroblastsMicrobial Sensitivity TestsStaphylococcus aureusTemperatureTime FactorsInhibitory Concentration 50Mice
Citations
442
FWCI
11.44
field-weighted impact
References
49
Percentile
99%
vs. same field & year
Citations per year
References
Disinfection, Sterilization, and Preservation
Soil Science · 1977 · 1,716 citations
Antiseptics and Disinfectants: Activity, Action, and Resistance
Clinical Microbiology Reviews · 1999 · 4,678 citations
Cationic antiseptics: diversity of action under a common epithet
Journal of Applied Microbiology · 2005 · 1,155 citations
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