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Expanded identification and characterization of mammalian circular RNAs

Genome biology · 2014 · Vol. 15(7) · pp. 409–409
Junjie U. GuoVikram AgarwalHuili GuoDavid P. Bartel

Abstract

Our results provide a new framework for future investigation of this intriguing topological isoform while raising doubts regarding a biological function of most circRNAs.

Circular RNAs in diseasesCancer-related molecular mechanisms researchRNA Research and SplicingBiologyHuman geneticsGenome BiologyComputational biologyIdentification (biology)Evolutionary biologyGeneticsComputational genomicsGenomicsGenome

MeSH terms

RNA, CircularAnimalsBase SequenceHumansMolecular Sequence DataPhylogenyPoriferaRNAGene ExpressionConserved SequenceSequence Analysis, RNAEvolution, MolecularComputational BiologyTrans-SplicingMicroRNAs

Funding

  • National Science Foundation
  • Howard Hughes Medical Institute
  • Damon Runyon Cancer Research Foundation
  • Agency for Science, Technology and Research
  • National Institutes of Health
Citations
1,611
FWCI
40.00
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References
32
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