article Open AccessTop 1% cited
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC‐1α
The EMBO Journal · 2007 · Vol. 26(7) · pp. 1913–1923
Zachary Gerhart‐Hines✉(Johns Hopkins University)Joseph T. Rodgers(Harvard University)Olivia Bare(Novartis (United States))Carles Lerín(Johns Hopkins Medicine)Seung-Hee Kim(Dana-Farber Cancer Institute)Raúl Mostoslavsky(Harvard University)Frederick W. Alt(Harvard University)Zhidan Wu(Novartis (Switzerland))Pere Puigserver(Johns Hopkins University)
Sirtuins and Resveratrol in MedicineAdipose Tissue and MetabolismEndoplasmic Reticulum Stress and DiseaseBiologyBeta oxidationMitochondrionSirtuin 1BiochemistryOxidative phosphorylationFatty acidPPARGC1AAcetylationPeroxisome
MeSH terms
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphap300-CBP-Associated FactorAcetyl-CoA C-AcyltransferaseAcetylationAnimalsCells, CulturedEnoyl-CoA HydrataseFibroblastsGlucoseMice, Inbred C57BLMitochondria, MuscleModels, BiologicalNiacinamideTranscription Factors3-Hydroxyacyl CoA Dehydrogenases
Funding
- U.S. Department of Defense
- American Diabetes Association
- Ellison Medical Foundation
- American Heart Association
- National Institutes of Health
Citations
1,271
FWCI
33.49
field-weighted impact
References
39
Percentile
100%
vs. same field & year
Citations per year
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References
Metabolic control through the PGC-1 family of transcription coactivators
Cell Metabolism · 2005 · 2,105 citations
The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes
Molecular and Cellular Biology · 2000 · 1,175 citations
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
Genes & Development · 1999 · 2,256 citations
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