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Alternative Complement Pathway in the Pathogenesis of Disease Mediated by Anti-Neutrophil Cytoplasmic Autoantibodies

American Journal Of Pathology · 2007 · Vol. 170(1) · pp. 52–64
Hong XiaoAdrian SchreiberPeter HeeringaRonald J. FalkJ. Charles Jennette
Vasculitis and related conditionsNeutrophil, Myeloperoxidase and Oxidative MechanismsInflammasome and immune disordersMyeloperoxidaseAutoantibodyImmunologyAlternative complement pathwayProteinase 3Complement systemGlomerulonephritisComplement factor BVasculitisImmune complex

MeSH terms

AnimalsCells, CulturedComplement Pathway, AlternativeDisease Models, AnimalGlomerulonephritisHumansImmunoglobulin GKidneyPeroxidaseGranulomatosis with PolyangiitisMice, KnockoutNeutrophil ActivationAntibodies, Antineutrophil CytoplasmicMiceMyeloblastin

Funding

  • Deutsche Forschungsgemeinschaft
  • National Institutes of Health
  • National Institute of Diabetes and Digestive and Kidney Diseases
Citations
557
FWCI
18.32
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
Cited by
Practice parameter for the diagnosis and management of primary immunodeficiency
Journal of Allergy and Clinical Immunology · 2015 · 761 citations
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