article Open AccessTop 1% cited

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Nature Methods · 2013 · Vol. 10(12) · pp. 1213–1218

Jason D. Buenrostro✉(Stanford University)Paul G. Giresi(Stanford University)Lisa C. Zaba(Stanford University)Howard Y. Chang(Stanford University)William J. Greenleaf(Stanford University)

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Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Immunotherapy and Immune ResponsesChromatinEpigenomicsNucleosomeTransposaseEpigenomeBiologyChIP-sequencingComputational biologyGeneticsDNA

MeSH terms

Cell SeparationChromatinDNA-Binding ProteinsEnhancer Elements, GeneticFlow CytometryHumansInterleukin-2NucleosomesTranscription FactorsCD4-Positive T-LymphocytesPolymerase Chain ReactionDimerizationComputational BiologyEpigenomics

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References

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

PLoS Biology · 2011 · 1,581 citations

High-Resolution Profiling of Histone Methylations in the Human Genome

Cell · 2007 · 6,869 citations

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Genome biology · 2009 · 22,766 citations

mRNA-Seq whole-transcriptome analysis of a single cell

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Cluster analysis and display of genome-wide expression patterns

Proceedings of the National Academy of Sciences · 1998 · 16,353 citations

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