reviewTop 1% cited
Role of Microglia in Inflammation-Mediated Neurodegenerative Diseases: Mechanisms and Strategies for Therapeutic Intervention
Journal of Pharmacology and Experimental Therapeutics · 2003 · Vol. 304(1) · pp. 1–7
Bin Liu✉(National Institutes of Health)Jau‐Shyong Hong
Neuroinflammation and Neurodegeneration MechanismsNuclear Receptors and SignalingMedicinal Plants and NeuroprotectionMicrogliaNeurodegenerationDiseaseNeuroscienceProinflammatory cytokineInflammationPathogenesisMedicineBiologyImmunology
MeSH terms
AnimalsAnti-Inflammatory AgentsDopamineHumansInflammationNaloxoneNerve DegenerationParkinson DiseaseMicrogliaNeuroprotective Agents
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References
Microglial activation‐mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease
Journal of Neurochemistry · 2002 · 688 citations
Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
The Journal of Immunology · 1992 · 1,117 citations
Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
Neurology · 1988 · 2,969 citations
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
Neuroscience · 1990 · 2,020 citations
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
Brain Research · 1992 · 942 citations
Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease
Neurobiology of Aging · 1988 · 736 citations
Microglia: a sensor for pathological events in the CNS
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