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Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study

Annals of the Rheumatic Diseases · 2013 · Vol. 73(7) · pp. 1340–1349
Gerry CoghlanChristopher P. DentonEkkehard GrünigDiana BondermanOliver DistlerDinesh KhannaUlf Müller‐LadnerJanet PopeMadelon C VonkMartin DoelbergHarbajan Chadha‐BorehamHarald HeinzlD RosenbergVallerie V. McLaughlinJames R. Seibold

Abstract

The novel, evidence-based DETECT algorithm for PAH detection in SSc is a sensitive, non-invasive tool which minimises missed diagnoses, identifies milder disease and addresses resource usage.

Pulmonary Hypertension Research and TreatmentsSystemic Sclerosis and Related DiseasesVenous Thromboembolism Diagnosis and ManagementMedicinePulmonary hypertensionReferralInternal medicineCardiologyNomogramMedical diagnosisRadiology

MeSH terms

AdultAgedAlgorithmsBreath TestsCross-Sectional StudiesEchocardiographyFemaleCardiac CatheterizationHumansHypertension, PulmonaryMaleMiddle AgedPulmonary Diffusing CapacityPulmonary Wedge PressureScleroderma, Systemic

Funding

  • Amgen
  • Bristol-Myers Squibb
  • Eli Lilly and Company
  • Pfizer
  • GlaxoSmithKline
  • Sanofi
  • Gilead Sciences
  • Teva Pharmaceutical Industries
  • Celgene
  • FibroGen
  • United Therapeutics Corporation
  • University of Michigan
  • Albert-Ludwigs-Universität Freiburg
  • Medac
  • Genentech
  • Division of Materials Research
  • Actelion Pharmaceuticals
Citations
806
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41.94
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41
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Cited by
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
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Definitions and Diagnosis of Pulmonary Hypertension
Journal of the American College of Cardiology · 2013 · 1,747 citations
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
European Respiratory Journal · 2022 · 1,919 citations
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