review Open AccessTop 1% cited

The efficiency of multi-target drugs: the network approach might help drug design

Trends in Pharmacological Sciences · 2005 · Vol. 26(4) · pp. 178–182

P CSERMELY✉(Semmelweis University)Vilmos Ágoston(HUN-REN Szegedi Biológiai Kutatóközpont)S. Pongor(International Centre for Genetic Engineering and Biotechnology)

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Computational Drug Discovery Methods Bioinformatics and Genomic Networks Protein Structure and DynamicsDrugDrug targetComputational biologyDrug discoveryComputer scienceDrug designDrug actionMachine learningPharmacologyMedicine

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799

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References

Emergence of Scaling in Random Networks

Science · 1999 · 35,882 citations

Efficient Behavior of Small-World Networks

Physical Review Letters · 2001 · 5,061 citations

Network motifs in the transcriptional regulation network of Escherichia coli

Nature Genetics · 2002 · 3,023 citations

Collective dynamics of ‘small-world’ networks

Nature · 1998 · 42,581 citations

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