reviewTop 1% cited

Glycolysis inhibition for anticancer treatment

Oncogene · 2006 · Vol. 25(34) · pp. 4633–4646

Hélène Pelicano✉(The University of Texas MD Anderson Cancer Center)Daniel Martín(Memorial Sloan Kettering Cancer Center)Rui‐Hua Xu(Sun Yat-sen University Cancer Center)Ping Huang(Center for Translational Molecular Medicine)

View via DOI Publisher page

Cancer, Hypoxia, and Metabolism Mitochondrial Function and Pathology ATP Synthase and ATPases ResearchGlycolysisWarburg effectBiologyCancer cellAnaerobic glycolysisCancerCancer researchTumor microenvironmentMetabolic pathwayCell biology

Funding

National Cancer Institute

Citations

1,500

FWCI

19.77

field-weighted impact

References

134

Percentile

99%

vs. same field & year

Citations per year

Cited by

Immunogenic Cell Death Activates the Tumor Immune Microenvironment to Boost the Immunotherapy Efficiency

Advanced Science · 2022 · 620 citations

3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs

Biotechnology and Bioengineering · 2018 · 676 citations

The Warburg Effect 97 Years after Its Discovery

Cancers · 2020 · 308 citations

Therapeutic Nanoparticles for Drug Delivery in Cancer

Clinical Cancer Research · 2008 · 2,887 citations

The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology

Journal of Physics D Applied Physics · 2012 · 1,474 citations

Regulation of the fructose transporter GLUT5 in health and disease

American Journal of Physiology-Endocrinology and Metabolism · 2008 · 472 citations

Anticonvulsant Mechanisms of the Ketogenic Diet

Epilepsia · 2007 · 507 citations

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders

Frontiers in Pharmacology · 2012 · 438 citations

References

THE METABOLISM OF TUMORS

The American Journal of the Medical Sciences · 1931 · 813 citations

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Cancer Cell · 2005 · 2,043 citations

On the Origin of Cancer Cells

Science · 1956 · 13,149 citations

Akt Stimulates Aerobic Glycolysis in Cancer Cells

Cancer Research · 2004 · 1,453 citations

Why do cancers have high aerobic glycolysis?

Nature reviews. Cancer · 2004 · 4,733 citations

Graded ATP depletion can cause necrosis or apoptosis of cultured mouse proximal tubular cells

American Journal of Physiology-Renal Physiology · 1998 · 375 citations

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

Journal of Experimental Biology · 2003 · 1,081 citations

Mitochondrial DNA mutations in human disease

Nature Reviews Genetics · 2005 · 1,831 citations

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

Science · 2009 · 15,796 citations

Citation Network

How this paper connects to the literature. Drag to explore, click any node to open that paper.