article Open AccessTop 1% cited

TopHat: discovering splice junctions with RNA-Seq

Bioinformatics · 2009 · Vol. 25(9) · pp. 1105–1111

Cole Trapnell✉(University of California, Berkeley)Lior Pachter(University of Maryland, College Park)Steven L. Salzberg(University of California, Berkeley)

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Abstract

Supplementary data are available at Bioinformatics online.

RNA Research and Splicing RNA and protein synthesis mechanisms RNA modifications and cancerspliceComputational biologyRNA-SeqComputer sciencePipeline (software)RNA splicingAnnotationRNAReference genomeSoftware

MeSH terms

AlgorithmsModels, GeneticRNA SplicingRNA, MessengerSoftwareSequence AlignmentSequence Analysis, RNAGene Expression Profiling

Funding

National Science Foundation

Citations

12,093

FWCI

107.29

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

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Genome Research · 2008 · 2,707 citations

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

Genome Research · 2008 · 2,821 citations

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Genome biology · 2009 · 22,766 citations

<tt>BLAT</tt>—The <tt>BLAST</tt>-Like Alignment Tool

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