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A Simple and Effective Chemical Phosphorylation Procedure for Biomolecules
Helvetica Chimica Acta · 1987 · Vol. 70(1) · pp. 175–186
Willi Bannwarth✉(Roche (Switzerland))Arnold Trzeciak(Roche (Switzerland))
Abstract
Abstract A general chemical phosphorylation method based on P(III) chemistry has been developed. The system is demonstrated for the phosphorylation of oligonucleotides, directly after their synthesis on a solid support, and for the O ‐phosphorylation of serine, threonine, and tyrosine as well as for a serine‐containing peptide.
RNA and protein synthesis mechanismsDNA and Nucleic Acid ChemistryChemical Synthesis and AnalysisChemistryPhosphorylationSerineBiomoleculeThreonineProtein phosphorylationOligonucleotideTyrosineTyrosine phosphorylationPeptide
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References
A simple, specific spray for the detection of phospholipids on thin-layer chromatograms
Journal of Lipid Research · 1964 · 2,150 citations
An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides
Tetrahedron Letters · 1983 · 511 citations
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