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Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection

International Journal of Cardiology · 2014 · Vol. 182 · pp. 349–360
Bin YuHa Won KimMin GongJingcai WangRonald W. MillardYigang WangMuhammad AshrafMeifeng Xu
Extracellular vesicles in diseaseMicroRNA in disease regulationCircular RNAs in diseasesCardioprotectionMicrovesiclesMedicineMesenchymal stem cellmicroRNACell biologyApoptosisStem cellCancer researchInternal medicine

MeSH terms

AnimalsCell SurvivalCells, CulturedGene Expression RegulationMyocardial InfarctionRNAApoptosisMyocytes, CardiacMicroRNAsMesenchymal Stem Cell TransplantationGATA4 Transcription FactorRatsExosomesMesenchymal Stem CellsReal-Time Polymerase Chain Reaction

Funding

  • Foundation for the National Institutes of Health
  • National Institutes of Health
Citations
474
FWCI
10.96
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42
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99%
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