reviewTop 1% cited

A role for local inflammation in the formation of drusen in the aging eye

American Journal of Ophthalmology · 2002 · Vol. 134(3) · pp. 411–431

Don H. Anderson✉(University of California, Santa Barbara)Robert F. Mullins(University of Iowa)Gregory S. Hageman(University of Iowa)Lincoln V. Johnson(University of California, Santa Barbara)

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Retinal Diseases and Treatments Barrier Structure and Function Studies Retinal Imaging and AnalysisDrusenMacular degenerationBasal laminaRetinal pigment epitheliumRetinalBiologyInflammationCell biologyMedicineOphthalmology

MeSH terms

AgingEye ProteinsHumansMacular DegenerationPigment Epithelium of EyeRetinitisRNA, MessengerRetinal DrusenMicroscopy, Confocal

Citations

1,089

FWCI

24.29

field-weighted impact

References

130

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100%

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References

Drusen associated with aging and age‐related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

The FASEB Journal · 2000 · 930 citations

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Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

Brain Research · 1991 · 1,150 citations

Inflammation and Alzheimer's disease

Neurobiology of Aging · 2000 · 4,492 citations

Drusen and Disciform Macular Detachment and Degeneration

Archives of Ophthalmology · 1973 · 591 citations

A Simplified Severity Scale for Age-Related Macular Degeneration

Archives of Ophthalmology · 2005 · 791 citations

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