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Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

European Journal of Pharmacology · 1990 · Vol. 185(1) · pp. 1–10
Ramón TrullásP. Skolnick
Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNeurotransmitter Receptor Influence on BehaviorNMDA receptorNeuroscienceLong-term potentiationGlutamate receptorAgonistPharmacologyAntidepressantLong-term depressionPartial agonistPsychology

MeSH terms

Amino AcidsAmino Acids, CyclicAnimalsAntidepressive AgentsBehavior, AnimalBrain ChemistryDose-Response Relationship, DrugImipramineImmobilizationMaleMice, Inbred C57BLMotor ActivitySynaptic TransmissionStress, PsychologicalStrychnine
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