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Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: I. Psychotropic Drugs

Journal of the American Geriatrics Society · 1999 · Vol. 47(1) · pp. 30–39
Rosanne M. LeipzigRobert G. CummingMary E. Tinetti

Abstract

There is a small, but consistent, association between the use of most classes of psychotropic drugs and falls. The evidence to date, however, is based solely on observational data, with minimal adjustment for confounders, dosage, or duration of therapy. The incidence of falls and their consequences in this population necessitate that future large randomized controlled trials of any medication in older persons should measure falls prospectively as an adverse outcome event.

Balance, Gait, and Falls PreventionCardiovascular Syncope and Autonomic DisordersStroke Rehabilitation and RecoveryMedicineOdds ratioMeta-analysisConfidence intervalPoison controlPsychiatrySedativeInjury preventionPsychotropic drugInternal medicine

MeSH terms

Accidental FallsAge FactorsAgedHumansPsychotropic DrugsResearch DesignRisk FactorsTime FactorsConfounding Factors, EpidemiologicIncidenceOdds RatioAge Distribution
Citations
1,149
FWCI
56.33
field-weighted impact
References
82
Percentile
100%
vs. same field & year
Citations per year
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Guideline for the Prevention of Falls in Older Persons
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References
Fall risk index for elderly patients based on number of chronic disabilities
The American Journal of Medicine · 1986 · 1,607 citations
Risk Factors for Falls among Elderly Persons Living in the Community
New England Journal of Medicine · 1988 · 6,520 citations
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