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Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study

Clinical Endocrinology · 2000 · Vol. 53(6) · pp. 733–737
Sandra KalmijnKala M. MehtaHuibert A. P. PolsAlbert HofmanHemmo A. DrexhageMonique M.B. Breteler

Abstract

This is the first prospective study to suggest that subclinical hyperthyroidism in the elderly increases the risk of dementia and Alzheimer's disease.

Thyroid Disorders and TreatmentsS100 Proteins and AnnexinsBone health and osteoporosis researchDementiaRotterdam StudySubclinical infectionMedicineInternal medicineProspective cohort studyPopulationEndocrinologyThyroid diseaseAlzheimer's disease

MeSH terms

AgedAlzheimer DiseaseAutoantibodiesDementiaFemaleFollow-Up StudiesHumansHyperthyroidismIodide PeroxidaseMaleMiddle AgedNetherlandsProspective StudiesRisk FactorsThyrotropin

Funding

  • Koninklijke Nederlandse Akademie van Wetenschappen
Citations
318
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Cited by
The Clinical Significance of Subclinical Thyroid Dysfunction
Endocrine Reviews · 2007 · 1,381 citations
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