article Open AccessTop 10% cited
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase
Diabetologia · 2009 · Vol. 52(7) · pp. 1409–1418
V. B. Matthews✉M.-B. Åström(Rigshospitalet)Stanley M. H. ChanClinton R. BruceK. S. Krabbe(Rigshospitalet)O. PrelovsekThorbjörn Åkerström(Rigshospitalet)Christina Yfanti(University of Copenhagen)Christa Broholm(University of Copenhagen)Ole Hartvig Mortensen(University of Copenhagen)Milena Penkowa(University of Copenhagen)Pernille Højman(University of Copenhagen)Alaa Zankari(University of Copenhagen)M. J. Watt(Monash University)Helle Brüünsgaard(Rigshospitalet)Bente Klarlund Pedersen(University of Copenhagen)Mark A. Febbraio
Nerve injury and regenerationMuscle Physiology and DisordersAdipose Tissue and MetabolismAMPKSkeletal muscleBrain-derived neurotrophic factorEndocrinologyInternal medicineProtein kinase ANeurotrophic factorsAMP-activated protein kinasePhosphorylationChemistry
MeSH terms
Acetyl-CoA CarboxylaseAnimalsCell LineExercise TestFatsHumansMaleMice, Inbred C57BLMuscle ContractionOxidation-ReductionPhosphorylationSignal TransductionGene ExpressionMuscle, SkeletalMuscle Fibers, Skeletal
Funding
- Diabetes Australia Research Trust
- Diabetes Australia
- National Research Foundation
- Danmarks Grundforskningsfond
- Lundbeckfonden
- Novo Nordisk
- Novo Nordisk Fonden
- H. Lundbeck A/S
- Medical Research Council
- Australian Research Council
- National Health and Medical Research Council
Citations
701
FWCI
8.24
field-weighted impact
References
45
Percentile
99%
vs. same field & year
Citations per year
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References
Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation
Thrombosis and Haemostasis · 2002 · 759 citations
The Effect of Acute Exercise on Serum Brain-Derived Neurotrophic Factor Levels and Cognitive Function
Medicine & Science in Sports & Exercise · 2007 · 823 citations
Brain-derived neurotrophic factor (BDNF) and type 2 diabetes
Diabetologia · 2006 · 694 citations
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Proceedings of the National Academy of Sciences · 1992 · 4,950 citations
Matrix metalloproteinases in brain development and remodeling: Synaptic functions and targets
Journal of Neuroscience Research · 2007 · 382 citations
Muscle‐derived interleukin‐6: mechanisms for activation and possible biological roles
The FASEB Journal · 2002 · 868 citations
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