reviewTop 1% cited
Transcriptional regulation of macrophage polarization: enabling diversity with identity
Nature reviews. Immunology · 2011 · Vol. 11(11) · pp. 750–761
Toby Lawrence✉(Centre d’Immunologie de Marseille-Luminy)Gioacchino Natoli(European Institute of Oncology)
Immune cells in cancerEpigenetics and DNA MethylationImmune Response and InflammationMacrophageBiologyMacrophage polarizationChromatinPhenotypeCell biologyFunction (biology)Transcriptional regulationGeneImmunology
MeSH terms
Interferon Regulatory Factor-4Gene Expression RegulationHumansMacrophagesPromoter Regions, GeneticProtein BindingPPAR gammaSTAT1 Transcription FactorSTAT6 Transcription FactorInterferon Regulatory Factors
Funding
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
Citations
2,247
FWCI
37.92
field-weighted impact
References
90
Percentile
100%
vs. same field & year
Citations per year
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References
Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression
The Journal of Immunology · 2006 · 2,322 citations
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
Nature Immunology · 2011 · 1,262 citations
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Proceedings of the National Academy of Sciences · 2010 · 4,451 citations
PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties
Cell Metabolism · 2007 · 1,284 citations
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Molecular Cell · 2010 · 14,269 citations
Monocyte and macrophage heterogeneity
Nature reviews. Immunology · 2005 · 5,112 citations
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Immunity · 2003 · 3,313 citations
Exploring the full spectrum of macrophage activation
Nature reviews. Immunology · 2008 · 8,962 citations
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