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The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

Immunity · 2011 · Vol. 35(6) · pp. 871–882

Ruoning Wang✉(St. Jude Children's Research Hospital)Christopher P. Dillon(St. Jude Children's Research Hospital)Lewis Z. Shi(St. Jude Children's Research Hospital)Sandra Milasta(St. Jude Children's Research Hospital)Robert Carter(St. Jude Children's Research Hospital)David Finkelstein(St. Jude Children's Research Hospital)Laura L. McCormick(St. Jude Children's Research Hospital)Patrick Fitzgerald(St. Jude Children's Research Hospital)Hongbo Chi(St. Jude Children's Research Hospital)Joshua Munger(University of Rochester)Douglas R. Green(St. Jude Children's Research Hospital)

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Cancer, Hypoxia, and Metabolism Pancreatic function and diabetes Metabolism, Diabetes, and CancerBiologyTranscription factorReprogrammingCell biologyCancer researchLymphocyte activationLymphocyte subsetsTranscription (linguistics)ImmunologyLymphocyte

MeSH terms

AnimalsGene Expression RegulationGlucoseGlutamineLymphocyte ActivationMice, Inbred C57BLOrnithinePolyaminesT-LymphocytesProto-Oncogene Proteins c-mycMice, KnockoutMiceHypoxia-Inducible Factor 1, alpha SubunitMetabolic Networks and PathwaysTOR Serine-Threonine Kinases

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