articleTop 1% cited

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

Biomaterials · 2010 · Vol. 31(13) · pp. 3657–3666

Chunbai He✉(State Key Laboratory of Genetic Engineering)Yiping Hu(Fudan University)Lichen Yin(Fudan University)Cui Tang(Fudan University)Chunhua Yin(State Key Laboratory of Genetic Engineering)

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Nanoparticle-Based Drug Delivery Advanced Drug Delivery Systems RNA Interference and Gene DeliveryBiodistributionSurface chargeMaterials scienceZeta potentialNanocarriersParticle sizeNanoparticleChitosanDrug carrierNanotechnology

MeSH terms

AnimalsCell LineHumansMacrophagesNeoplasms, ExperimentalParticle SizePolymersSurface PropertiesTissue DistributionMiceNanoparticles

Funding

National Natural Science Foundation of China

Citations

2,520

FWCI

36.32

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

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References

Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells

Nano Letters · 2006 · 4,818 citations

Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs

Biomaterials · 2004 · 1,432 citations

Nanoparticle therapeutics: an emerging treatment modality for cancer

Nature Reviews Drug Discovery · 2008 · 4,194 citations

Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model

International Journal of Pharmaceutics · 2005 · 881 citations

Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis

Biochemical Journal · 2004 · 2,791 citations

Chitosan and Its Use as a Pharmaceutical Excipient

Pharmaceutical Research · 1998 · 1,392 citations

Nanoparticles in cellular drug delivery

Bioorganic & Medicinal Chemistry · 2009 · 884 citations

Size Effect on Cell Uptake in Well‐Suspended, Uniform Mesoporous Silica Nanoparticles

Small · 2009 · 1,021 citations

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