articleTop 1% cited
Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
Neuroscience Letters · 1992 · Vol. 147(1) · pp. 58–62
Diane P. Hanger✉Kenneth Hughes(Ludwig Cancer Research)James R. Woodgett(Ludwig Cancer Research)Jean‐Pierre Brion(Université Libre de Bruxelles)Brian H. Anderton
Alzheimer's disease research and treatmentsWnt/β-catenin signaling in development and cancerMicrotubule and mitosis dynamicsGSK-3Glycogen synthaseKinasePhosphorylationGSK3BAlzheimer's diseaseEpitopeChemistryBiologyCell biology
MeSH terms
Alzheimer DiseaseBrain ChemistryElectrophoresis, Polyacrylamide GelHippocampusHumansIntermediate FilamentsNeuronsPhosphorylationProtein KinasesRecombinant ProteinsBlotting, Westerntau ProteinsCalcium-Calmodulin-Dependent Protein KinasesGlycogen Synthase Kinases
Citations
728
FWCI
13.32
field-weighted impact
References
38
Percentile
99%
vs. same field & year
Citations per year
Cited by
GSK-3: tricks of the trade for a multi-tasking kinase
Journal of Cell Science · 2003 · 2,066 citations
Neurodegenerative Tauopathies
Annual Review of Neuroscience · 2001 · 2,357 citations
GSK3 takes centre stage more than 20 years after its discovery
Biochemical Journal · 2001 · 1,294 citations
Roles of tau protein in health and disease
Acta Neuropathologica · 2017 · 951 citations
Activation of the Wnt Signaling Pathway: A Molecular Mechanism for Lithium Action
Developmental Biology · 1997 · 642 citations
The GSK3 hypothesis of Alzheimer’s disease
Journal of Neurochemistry · 2007 · 1,179 citations
Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells
Current Biology · 1996 · 1,319 citations
References
Molecular cloning and expression of glycogen synthase kinase-3/factor A.
The EMBO Journal · 1990 · 1,349 citations
The distribution of tau in the mammalian central nervous system.
The Journal of Cell Biology · 1985 · 1,596 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
