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Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Immunity · 1998 · Vol. 9(1) · pp. 143–150
Osamu AdachiTaro KawaiKiyoshi TakedaMakoto MatsumotoHiroko TsutsuiMasafumi SakagamiKenji NakanishiShizuo Akira
Immune Response and InflammationInflammasome and immune disordersNF-κB Signaling PathwaysBiologySignal transducing adaptor proteinSignal transductionCell biologyReceptorInterleukin-1 receptorKinaseFunction (biology)Cancer researchImmunology

MeSH terms

AnimalsAntigens, DifferentiationCells, CulturedDNAEnzyme ActivationFemaleHumansInterleukin-1MaleMice, Inbred C57BLProteinsReceptors, ImmunologicCytokinesNF-kappa BCalcium-Calmodulin-Dependent Protein Kinases
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References
Biologic basis for interleukin-1 in disease
Blood · 1996 · 4,341 citations
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