articleTop 1% cited
A function for interleukin 2 in Foxp3-expressing regulatory T cells
Nature Immunology · 2005 · Vol. 6(11) · pp. 1142–1151
Jason D. Fontenot✉(Seattle University)Jeffrey P. Rasmussen(University of Washington)Marc A. Gavin(Howard Hughes Medical Institute)Alexander Y. Rudensky(Seattle University)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesIL-2 receptorFOXP3Cell biologyRegulatory T cellT cellBiologyImmune systemSignal transductionZAP70Immunology
MeSH terms
AnimalsCell DifferentiationDNA-Binding ProteinsGene Expression RegulationHomeostasisImmune ToleranceInterleukin-2Lymphocyte ActivationMutationT-LymphocytesReceptors, Interleukin-2Signal TransductionGreen Fluorescent ProteinsMiceForkhead Transcription Factors
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References
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
Nature Genetics · 2001 · 2,563 citations
Interleukin‐2 is essential for CD4<sup>+</sup>CD25<sup>+</sup> regulatory T cell function
European Journal of Immunology · 2004 · 530 citations
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Nature Immunology · 2003 · 7,605 citations
Gene Ontology: tool for the unification of biology
Nature Genetics · 2000 · 43,975 citations
An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation
The Journal of Experimental Medicine · 1999 · 1,584 citations
Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3
Immunity · 2005 · 2,235 citations
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
The Journal of Experimental Medicine · 2000 · 2,205 citations
Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation
The Journal of Experimental Medicine · 2000 · 2,174 citations
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