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Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer
New England Journal of Medicine · 2002 · Vol. 347(16) · pp. 1233–1241
Bernard Fisher✉(University of Pittsburgh)Stewart Anderson(NSABP Foundation)John Bryant(NSABP Foundation)Richard G. Margolese(NSABP Foundation)Melvin Deutsch(University of Pittsburgh)Edwin R. Fisher(NSABP Foundation)Jong‐Hyeon Jeong(NSABP Foundation)Norman Wolmark(NSABP Foundation)
Abstract
Lumpectomy followed by breast irradiation continues to be appropriate therapy for women with breast cancer, provided that the margins of resected specimens are free of tumor and an acceptable cosmetic result can be obtained.
Breast Cancer Treatment StudiesBreast Lesions and CarcinomasBreast Implant and ReconstructionLumpectomyMedicineHazard ratioMastectomyCumulative incidenceBreast cancerConfidence intervalTotal MastectomyRadiation therapySurgery
MeSH terms
Breast NeoplasmsCombined Modality TherapyFemaleFollow-Up StudiesHumansNeoplasm InvasivenessNeoplasm Recurrence, LocalMastectomy, RadicalMastectomy, SegmentalIncidenceSurvival AnalysisRandomized Controlled Trials as TopicNeoplasms, Second PrimaryDisease-Free Survival
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