articleTop 1% cited
The Metabolic Syndrome and Total and Cardiovascular Disease Mortality in Middle-aged Men
JAMA · 2002 · Vol. 288(21) · pp. 2709–2709
Hanna‐Maaria Lakka✉(University of Eastern Finland)
Abstract
Cardiovascular disease and all-cause mortality are increased in men with the metabolic syndrome, even in the absence of baseline CVD and diabetes. Early identification, treatment, and prevention of the metabolic syndrome present a major challenge for health care professionals facing an epidemic of overweight and sedentary lifestyle.
Diabetes, Cardiovascular Risks, and LipoproteinsCardiovascular Function and Risk FactorsDiabetes Treatment and ManagementMedicineMetabolic syndromeDyslipidemiaInternal medicineNational Cholesterol Education ProgramDiabetes mellitusAbdominal obesityProspective cohort studyOverweightPopulation
MeSH terms
Cardiovascular DiseasesCause of DeathCoronary DiseaseFactor Analysis, StatisticalHumansMaleMiddle AgedRisk FactorsCohort StudiesProportional Hazards ModelsSurvival AnalysisMetabolic Syndrome
Citations
5,055
FWCI
123.91
field-weighted impact
References
42
Percentile
100%
vs. same field & year
Citations per year
Cited by
Increasing Prevalence of the Metabolic Syndrome Among U.S. Adults
Diabetes Care · 2004 · 1,496 citations
Minireview: Adiposity, Inflammation, and Atherogenesis
Endocrinology · 2003 · 756 citations
Definition of Metabolic Syndrome
Circulation · 2004 · 5,942 citations
Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited
Arteriosclerosis Thrombosis and Vascular Biology · 2004 · 1,368 citations
Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss
Circulation · 2005 · 3,147 citations
Risks for All-Cause Mortality, Cardiovascular Disease, and Diabetes Associated With the Metabolic Syndrome
Diabetes Care · 2005 · 1,699 citations
Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity
Hypertension · 2004 · 1,065 citations
The Metabolic Syndrome
Endocrine Reviews · 2008 · 2,088 citations
References
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU study
Diabetologia · 2001 · 1,118 citations
Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome
Diabetes Care · 2001 · 4,771 citations
Epidemiology of coronary heart disease: The Framingham study
The American Journal of Medicine · 1984 · 1,050 citations
Prevalence of the Metabolic Syndrome Among US Adults
JAMA · 2002 · 6,709 citations
Role of Insulin Resistance in Human Disease
Diabetes · 1988 · 12,123 citations
Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
JAMA · 1993 · 27,890 citations
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin
New England Journal of Medicine · 2002 · 18,892 citations
Mortality from Coronary Heart Disease in Subjects with Type 2 Diabetes and in Nondiabetic Subjects with and without Prior Myocardial Infarction
New England Journal of Medicine · 1998 · 7,049 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.