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A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals
The American Journal of Human Genetics · 2009 · Vol. 84(2) · pp. 210–223
Brian L. Browning✉(University of Auckland)Sharon R. Browning(University of Auckland)
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and AnimalsImputation (statistics)HaplotypeInferenceGenotypeComputer scienceStatisticsMissing dataBiologyData miningGenetics
MeSH terms
Computer SimulationFemaleGene FrequencyGenotypeHaplotypesHumansMaleMarkov ChainsModels, GeneticNuclear FamilyReproducibility of Results
Funding
- Wellcome Trust
- National Institutes of Health
Citations
1,695
FWCI
50.09
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References
30
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100%
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References
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The American Journal of Human Genetics · 2001 · 1,311 citations
A New Statistical Method for Haplotype Reconstruction from Population Data
The American Journal of Human Genetics · 2001 · 7,519 citations
A Fast and Flexible Statistical Model for Large-Scale Population Genotype Data: Applications to Inferring Missing Genotypes and Haplotypic Phase
The American Journal of Human Genetics · 2006 · 2,021 citations
A tutorial on hidden Markov models and selected applications in speech recognition
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International Journal of Epidemiology · 2005 · 1,005 citations
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Nature · 2007 · 9,601 citations
Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering
The American Journal of Human Genetics · 2007 · 3,489 citations
A new multipoint method for genome-wide association studies by imputation of genotypes
Nature Genetics · 2007 · 2,704 citations
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