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Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress

Cell Metabolism · 2007 · Vol. 6(4) · pp. 280–293
Tim J. SchulzKim ZarseAnja VoigtNadine UrbanMarc BirringerMichael Ristow
Genetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninCalorie restrictionBiologyOxidative stressCaenorhabditis elegansReactive oxygen speciesMitochondrionAMPKLongevitySIRT3Mitochondrial ROS

MeSH terms

AnimalsGlucoseGlycolysisLongevityMitochondriaMultienzyme ComplexesCaenorhabditis elegansProtein Serine-Threonine KinasesReactive Oxygen SpeciesOxidative StressCell RespirationCaenorhabditis elegans ProteinsSirtuinsAMP-Activated Protein Kinases
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Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress · Scinovex