articleTop 10% cited
Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
Neuroscience Letters · 2010 · Vol. 486(3) · pp. 235–239
Shankar J. Chinta(Buck Institute for Research on Aging)Jyothi K. Mallajosyula(Buck Institute for Research on Aging)Anand Rane(Buck Institute for Research on Aging)Julie K. Andersen✉(Buck Institute for Research on Aging)
Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyAlzheimer's disease research and treatmentsMitophagyMitochondrionCell biologyDopaminergicBiologyAlpha-synucleinIn vivoAutophagyBiochemistryChemistry
MeSH terms
AgingAnimalsAutophagyDisease Models, AnimalDopamineMice, TransgenicNeuronsParkinson DiseaseSubstantia NigraElectron Transport Complex IProteasome Endopeptidase ComplexMitochondrial MembranesMicealpha-SynucleinProteasome Inhibitors
Funding
- National Institutes of Health
Citations
435
FWCI
12.10
field-weighted impact
References
32
Percentile
99%
vs. same field & year
Citations per year
Cited by
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Frontiers in Neuroscience · 2016 · 374 citations
References
MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE
Annual Review of Neuroscience · 2005 · 1,280 citations
AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease
Nature Genetics · 1998 · 3,865 citations
Selective degradation of mitochondria by mitophagy
Archives of Biochemistry and Biophysics · 2007 · 1,506 citations
Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease
Science · 1997 · 8,181 citations
Mitochondria take center stage in aging and neurodegeneration
Annals of Neurology · 2005 · 949 citations
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