reviewTop 1% cited
DNA hypermethylation in tumorigenesis: epigenetics joins genetics
Trends in Genetics · 2000 · Vol. 16(4) · pp. 168–174
Stephen B. Baylin✉(Johns Hopkins University)James G. Herman✉(Johns Hopkins University)
Epigenetics and DNA MethylationCancer-related gene regulationGenomics and Chromatin DynamicsBiologyEpigeneticsDNA methylationGeneticsCarcinogenesisChromatinEpigenetics of physical exerciseCancer epigeneticsGeneEpigenomics
MeSH terms
DNA, NeoplasmHumansNeoplasmsDNA Methylation
Funding
- National Cancer Institute
Citations
1,634
FWCI
41.02
field-weighted impact
References
92
Percentile
100%
vs. same field & year
Citations per year
Cited by
Histone deacetylases (HDACs): characterization of the classical HDAC family
Biochemical Journal · 2003 · 3,077 citations
Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
Nutrients · 2011 · 585 citations
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Nature Genetics · 2003 · 6,253 citations
DNA methylation patterns and epigenetic memory
Genes & Development · 2002 · 7,054 citations
Methylation matters
Journal of Medical Genetics · 2001 · 437 citations
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
Human Molecular Genetics · 2001 · 941 citations
The fundamental role of epigenetic events in cancer
Nature Reviews Genetics · 2002 · 5,646 citations
Epigenetic factors in aging and longevity
Pflügers Archiv - European Journal of Physiology · 2009 · 334 citations
References
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Nature Genetics · 1998 · 2,718 citations
Cancer-epigenetics comes of age
Nature Genetics · 1999 · 2,354 citations
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences · 1996 · 5,649 citations
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Cell · 1999 · 6,039 citations
Histone acetylation and transcriptional regulatory mechanisms
Genes & Development · 1998 · 1,819 citations
Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors
JNCI Journal of the National Cancer Institute · 2000 · 1,215 citations
Related articles
DNA methylation landscapes: provocative insights from epigenomics
Nature Reviews Genetics · 2008 · 3,047 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.
