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Effect of chitosan on epithelial permeability and structure

International Journal of Pharmaceutics · 1999 · Vol. 182(1) · pp. 21–32

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Barrier Structure and Function Studies Advanced Drug Delivery Systems Proteins in Food SystemsChitosanTrypan blueParacellular transportBiophysicsChemistryTight junctionViability assayOccludinPermeability (electromagnetism)Cell

MeSH terms

AnimalsBiocompatible MaterialsBiological TransportCell Membrane PermeabilityChitinDose-Response Relationship, DrugFluorescent DyesHumansIntestinal AbsorptionIntestinal MucosaMembrane ProteinsMicroscopy, ElectronPhosphoproteinsRabbitsStructure-Activity Relationship

Citations

570

FWCI

5.71

field-weighted impact

References

16

Percentile

96%

vs. same field & year

Citations per year

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References

Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2)

Pharmaceutical Research · 1994 · 768 citations

Chitosan as a Novel Nasal Delivery System for Peptide Drugs

Pharmaceutical Research · 1994 · 620 citations

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Gastroenterology · 1989 · 2,193 citations

Occludin: a novel integral membrane protein localizing at tight junctions.

The Journal of Cell Biology · 1993 · 2,521 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

The Journal of Cell Biology · 1986 · 1,617 citations

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