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FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

Nature Cell Biology · 2004 · Vol. 6(2) · pp. 154–161

Donna J. Webb✉(University of Virginia)Karen Donais(University of Virginia)Leanna Whitmore(University of Virginia)Sheila Μ. Thomas(Center for Cancer Research)Christopher E. Turner(SUNY Upstate Medical University)J. Thomas Parsons(University of Virginia)Alan F. Horwitz(University of Virginia)

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Cell Adhesion Molecules Research Cellular Mechanics and Interactions Wnt/β-catenin signaling in development and cancerPaxillinFocal adhesionCell biologyProto-oncogene tyrosine-protein kinase SrcCell adhesionMyosin light-chain kinaseKinaseAdhesionPTK2Cell adhesion molecule

MeSH terms

AnimalsCell AdhesionCell MovementCytoskeletal ProteinsFibroblastsMyosin-Light-Chain KinasePhosphoproteinsProtein-Tyrosine KinasesProteinsRecombinant Fusion ProteinsSignal Transductionsrc-Family KinasesMitogen-Activated Protein KinasesAdaptor Proteins, Vesicular TransportRetinoblastoma-Like Protein p130

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MAP kinases and cell migration