article Open AccessTop 1% cited
Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
Cancer Cell · 2009 · Vol. 15(6) · pp. 501–513
Zhizhong Li✉(Duke Medical Center)Shideng Bao(Cleveland Clinic)Qiulian Wu(Cleveland Clinic)Hui Wang(Duke Medical Center)Christine E. Eyler(Duke Medical Center)Sith Sathornsumetee(Duke Medical Center)Qing Shi(Duke Medical Center)Yiting Cao(Duke Medical Center)Justin D. Lathia(Cleveland Clinic)Roger E. McLendon(Duke Medical Center)Anita B. Hjelmeland(Cleveland Clinic)Jeremy N. Rich(Cleveland Clinic)
Cancer, Hypoxia, and MetabolismCancer Cells and MetastasisGlioma Diagnosis and TreatmentHypoxia (environmental)GliomaStem cellBiologyCancer researchCell biologyHypoxia-inducible factorsGeneChemistryGenetics
MeSH terms
Endothelial PAS Domain-Containing Protein 1AnimalsBrain NeoplasmsCell SurvivalCells, CulturedGlioblastomaHumansMice, Inbred BALB CMice, NudeNeoplasm TransplantationNeovascularization, PathologicStem CellsBiomarkers, TumorNeoplastic Stem CellsCell Hypoxia
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1,308
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67
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100%
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References
Hypoxia — a key regulatory factor in tumour growth
Nature reviews. Cancer · 2002 · 5,147 citations
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer
Journal of Cellular Physiology · 2004 · 1,237 citations
CD133+ and CD133− Glioblastoma-Derived Cancer Stem Cells Show Differential Growth Characteristics and Molecular Profiles
Cancer Research · 2007 · 1,137 citations
Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma
Molecular and Cellular Biology · 2005 · 929 citations
Stem cells, cancer, and cancer stem cells
Nature · 2001 · 9,682 citations
Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma
Cancer Research · 2004 · 2,577 citations
Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4
Cell stem cell · 2007 · 1,036 citations
A Perivascular Niche for Brain Tumor Stem Cells
Cancer Cell · 2007 · 2,168 citations
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